When you’ve received a new order, you don’t need to press Request Fulfillment to process it on Shopify; you can go to the Zopi app to fulfill it. As a third-party fulfillment service, Zopi will sync your order to the app and assist you in fulfilling orders with some simple clicks. Refer to this article for detailed steps.
Even if you request fulfillment for an order in Shopify and the status changed to Fulfillment In Progress, the order will not be affected in Zopi and you can deal with it like you normally do.